Received: 19 Sep 2018
Revised: 25 Oct 2018
Accepted: 28 Oct 2018
Published online: 29 Oct 2018

Nanoparticles in Biomedicine-Focus on Imaging Applications

Peng Zhou,2,# Juping Wang,3,# Xiaohong Du,5 Tao Huang,6 Prakash D. Nallathamby,7 Lan Yang,1 Weiwei Zou,1 Yongchao Zhou,1 Jean-Michel Jault,8 Song Chen4,* and Feng Ding1,*

1 Department of Microbiology & Immunology, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou 325035, China

2 Department of Anatomy, School of Basic Medical Sciences, Wenzhou Medical University, Wenzhou 325035, China

3 Department of Pathophysiology, School of Basic Medical Sciences, Youjiang Medical University for Nationalities, Baise, Guangxi 533000, China

4 Institute of Medicinal Biotechnology, Jiangsu College of Nursing, Huaian, Jiangsu 223005, China

5 Center of Systems Medicine, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100005; Suzhou Institute of Systems Medicine, Suzhou, Jiangsu 215123, China.

6 Department of Chemistry, Savannah State University, Savannah, GA31404, USA

7 Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA

8 UMR5086 CNRS/UCBLyon I, MMSB-IBCP, 7 Passage du Vercors 69367 Lyon cedex 07, France

#-equal contribution

*E-mail: (F. Ding); (S. Chen)


Over the last two decades, nanotechnology has become one of the most dynamically evolving fields of research. Various types of nanoparticles are widely exploited to extend our understanding of biological interactions at the molecular level. They are actively engaged in the biomedical research for imaging, biosensing, drug delivery and/or concurrent therapy. Recent progress on this field is briefly reviewed here with an emphasis on the wide imaging applications of nanoparticles. Collectively, this field will no doubt make a greater impact after we gradually address any potential risk of nanoparticles.

Keywords: Nanoparticles; Biomedical application; Imaging; Biosensing; Drug delivery; Therapy