Multifunctional Polymer Nanocomposites for Non-Enzymatic Glucose Detection: A Brief Review

Bo Wu1

Qizhou Xue2

Yuxin Fan2

Dapeng Cui1,Email

Yunlong Sun1

Ben Bin Xu3

Huige Wei1,Email

Handong Li3

Priyanka Wasnik3

Deepak Sridhar4

Hassan Algadi5

Zhanhu Guo3,Email

Sri Hari Kumar Annamareddy6,Email

1College of Light Industry Science and Engineering, Tianjin University of Science and Technology, Tianjin, 300457, China
2Tianjin Key Laboratory of Brine Chemical Engineering and Resource Eco-utilization, College of Chemical Engineering and Materials Science, Tianjin University of Science and Technology, Tianjin, 300457, China
3Department of Mechanical and Construction Engineering, Faculty of Engineering and Environment, Northumbria University, Newcastle upon Tyne, NE1 8ST, UK
4Zentek Ltd. 24 Corporate Crt, Guelph, Ontario, N1G 5G5 Canada
5Department of Electrical Engineering, Faculty of Engineering, Najran University, Najran, 11001, Saudi Arabia
6Department of Chemical and Petrochemical Engineering, University of Nizwa, Birkat Al-Mouz 616, Sultanate of Oman.

Abstract

Glucose sensors have been widely used for clinical diagnostics, environmental monitoring, and food industries. Traditional enzymatic glucose sensors are limited for practical applications due to the restriction of enzymes. In this context, non-enzymatic glucose sensors with metal nanoparticles as redox centers have become a prominent area of current research. However, the catalytic activity of metal nanoparticles is limited by their agglomeration and poor conductivity. In recent years, combining metal nanoparticles with highly conductive polymers to prepare multifunctional polymer nanocomposites (MPNCs) has become a popular strategy to overcome these problems. In this paper, the most recent progress in MPNCs for non-enzymatic glucose detection are briefly reviewed, and the challenges and perspectives are also discussed.

Multifunctional Polymer Nanocomposites for Non-Enzymatic Glucose Detection: A Brief Review