Complexation of Antibiotics with Transition Metal Ions: A Review
Naresh Chouhan, Milan Hait, Gourisankar Roymahapatra, Mina Huang, Ben Bin Xu and Zhanhu Guo
1 Department of Chemistry, ISBM University, Gariyaband (C.G.), 493996, India
2 Department of Chemistry, Dr. C.V. Raman University, Kargi Road, Kota, Bilaspur, Chhattisgarh, 495113, India
3 School of Applied Sciences and Humanities, Haldia Institute of Technology, Haldia, West Bengal, 721657, India
4 Advanced Materials Division, Engineered Multifunctional Composites (EMC) Nanotech. LLC, Knoxville, TN, 37934, USA
5 Integrated Composites Laboratory (ICL), Department of Chemical & Biomolecular Engineering, University of Tennessee, Knoxville, TN, 37996, USA
6 Mechanical and Construction Engineering, Faculty of Engineering and Environment, Northumbria University, Newcastle upon Tyne NE1 8ST, UK
Abstract
One of the most significant chemical processes for forming complexes is complexation. Various thermodynamic changes occur during the creation of complexes, which have been examined at various temperatures using various methodologies. The goal of this paper is to provide a general overview of antibiotic-metal ion interactions. How does vary the stability constants and it influences the complex formation. In terms of biological significance, changes in the values of thermodynamic properties like free energy (ΔGo), enthalpy (ΔHo), and entropy (ΔSo) are far more crucial to the development of complexes. This study is very useful for complexation properties as well as stabilities of antibiotics with metal ions.
Publication details
Received: 06 Feb 2022
Revised: 17 Feb 2022
Accepted: 18 Feb 2022
Published online: 23 Feb 2022
Article type:
Review Paper
DOI:
10.30919/esfaf665
Volume:
8
Page:
1-11
Citation:
ES Food and Agroforestry, 2022, 8, 1-11
Permissions:
Copyright
Number of downloads:
10076
Citation Information:
11
Description:
Complexation of anti-toxins with metal particles. Antibiotics structures, properties and natura....
Complexation of anti-toxins with metal particles. Antibiotics structures, properties and natural meanings. Stability constants and thermodynamic boundaries at various temperatures.
This article is cited by 11 publications.
- Aratrika Samajdar, Supriyo Halder, Sukanya Chatterjee, Debjeet Chakraborty, Debapriya Maitra, Bedaprana Roy, Arup Kumar Mitra, Anindita Banerjee, Bikash Kumar Panda, Kausikisankar Pramanik, Sanjib Ganguly. Synthesis, Molecular Structure, and Antibacterial Efficacies of Transition Metal Azo‐Oximates of Fe(II) and Mn(II), a Sustainable Solution to Multidrug Resistance in Bacteria. Biotechnology and Applied Biochemistry 2026, 73, 1217, DOI: 10.1002/bab.70090
- Yangkai Zhang, Liu Cao, Haibin Fu, Min Zhang, Jun Meng, Jalal T. Althakafy, Hala M. Abo-Dief, Salah M. El-Bahy, Yushun Zhang, Huanhuan Wei, Ben Bin Xu, Zhanhu Guo. Effect of sulfamethazine on anaerobic digestion of manure mediated by biochar. Chemosphere 2022, 306, 135567, DOI: 10.1016/j.chemosphere.2022.135567
This article is cited by 11 publications.
- Aratrika Samajdar, Supriyo Halder, Sukanya Chatterjee, Debjeet Chakraborty, Debapriya Maitra, Bedaprana Roy, Arup Kumar Mitra, Anindita Banerjee, Bikash Kumar Panda, Kausikisankar Pramanik, Sanjib Ganguly. Synthesis, Molecular Structure, and Antibacterial Efficacies of Transition Metal Azo‐Oximates of Fe(II) and Mn(II), a Sustainable Solution to Multidrug Resistance in Bacteria. Biotechnology and Applied Biochemistry 2026, 73, 1217, DOI: 10.1002/bab.70090
- Yangkai Zhang, Liu Cao, Haibin Fu, Min Zhang, Jun Meng, Jalal T. Althakafy, Hala M. Abo-Dief, Salah M. El-Bahy, Yushun Zhang, Huanhuan Wei, Ben Bin Xu, Zhanhu Guo. Effect of sulfamethazine on anaerobic digestion of manure mediated by biochar. Chemosphere 2022, 306, 135567, DOI: 10.1016/j.chemosphere.2022.135567
- Haoran Ji, Guilin He, Wenxuan Ji, Zeyang Ren, Zeting Chen, Baozhen Liu, Yonglei Wang. Environmental fate and ecotoxicological behavior of complex contamination of antibiotics and metal ions in aquatic systems. Water Environment Research 2025, 97, , DOI: 10.1002/wer.70074
- Ki Joon Heo, Dong Uk Lee, Jae Hak Shin, Junghun Park, Byeong Jin Lee, Juhun Shin, Sang Bin Jeong, Gi Byoung Hwang, Alexander J. MacRobert, Ivan P. Parkin, Jae Hee Jung, Dong Yun Choi. Transparent, Robust, and Photochemical Antibacterial Surface Based on Hydrogen Bonding between a Si-Al and Cationic Dye. ACS Applied Materials & Interfaces 2022, 14, 53285, DOI: 10.1021/acsami.2c16071
- Wannapa Phunswat, Laddawan Buddeekul, Poomipat Tamdee, Jitnapa Sirirak, Nichanun Sirasunthorn. Modulation of Papain Activity via Copper-Abamectin Complexation for Enhanced Biosensor Performance in Pesticide Detection. ACS Agricultural Science & Technology 2025, 5, 2284, DOI: 10.1021/acsagscitech.5c00684
- Yiming Zhong, Yunchen Long, Yinuo Sun, Jiachen Qin, Yongxin Li, Gemeng Liang, Jinshuo Zou, Peitao Xie. Ultra-lightweight carbon nanocomposites as microwave absorber with high absorbing performance derived from flour. Advanced Composites and Hybrid Materials 2025, 8, , DOI: 10.1007/s42114-024-01080-5
- Jia-Qi Hu, Jing Wang, Zhen-Hua Shen, Yu-Xian Lai, Jia-Yin You, Qiang Yan, Ke-Feng Ren, Jian Ji. Mechanical Enhancement of the Gelatin/Poly(zinc acrylate) Hydrogel Stent in Bile. ACS Applied Bio Materials 2023, 6, 5621, DOI: 10.1021/acsabm.3c00786
- Tingting Xi, Chaojian Li, Yaqian Yu, Weiqi Wei, Sha Wang, Tingting Xu, Huining Xiao, Hongqi Dai, Xuelian Zhou, Huiyang Bian. In-situ deposition of β-FeOOH nanoparticles on commercially available filter paper for fast and efficient removal of antibiotic. Advanced Composites and Hybrid Materials 2025, 8, , DOI: 10.1007/s42114-025-01212-5
- Elsayed M. AbouElleef, Rania A. Saad, M. A. Diab, M. M. El-Zahed, A. Z. El-Sonbati, Sh. M. Morgan. Synthesis, characterization, biological evaluation and molecular docking of a Schiff base ligand and its metal complexes. BioMetals 2025, 38, 935, DOI: 10.1007/s10534-025-00688-4
- Lihong Cao, Chen Li, Fazhi Zhang, Xiaoxiao Guo, Xiaodong Lei, Yiping Wang. MgAlFe-Mixed Metal Oxides Derived from Layered Double Hydroxides Enhanced Peroxydisulfate Activation for Ciprofloxacin Degradation via an Electron Transfer Mechanism. Industrial & Engineering Chemistry Research 2025, 64, 9036, DOI: 10.1021/acs.iecr.5c00333
- Sandra Brzeska, Paulina Truszkowska, Magdalena Stasiuk, Mariusz Makowski. Metal–Sulfonamide Interactions as an Overlooked Factor in Analytical Monitoring and Degradation Studies. Critical Reviews in Analytical Chemistry 2026, , 1, DOI: 10.1080/10408347.2026.2743807
General Links :
Copyright © 2026 Engineered Science Publisher, All Rights Reserved