The quality changes of Carassius auratus in different pressure and low temperature storage conditions were investigated in this paper. Fresh Carassius auratus were vacuum pre-cooled and then were stored in different hypobaric storage conditions for about 12 days. Key indicators of quality changes, such as sensory scores and total number of colonies were collected. The microorganism growth under experimental conditions were described using the Gompertz equation. The research results show that, the shelf life of fresh Carassius auratus under atmospheric refrigeration is about 6 days. While the shelf life of fresh Carassius auratus under hypobaric refrigeration at 4 kPa and 3.5 kPa is 10 and 12 days, respectively. In the experiment, the sensory scores in each storage condition were on decline. However, the total number of colonies collected in the experiment increased at different rates. The total number of colonies in fresh Carassius auratus refrigerated at normal pressure for 12 days was 6.561 lg CFU/g; while under hypobaric at 4 kPa for 12 days, that was 5.857 lg CFU/g and 5.339 lg CFU/g at 3.5 kPa, respectively. The Gomportz model can accurately predict the dynamic changes of the total number of colonies in flesh Carassius auratus under hypobaric storage.