High-Sensitivity Electrochemical Detection of Chlorogenic Acid Based on Pt@r-GO@MWCNTs Ternary Nanocomposites Modified Electrodes

Y. Bakytkarim1,#,Email

S. Tursynbolat2,#,Email

Zh. S. Mukatayeva1,Email

Ye. Tileuberdi1,Email

N.A. Shadin1

Zh.M. Assirbayeva1,Email

L.S. Wang3

L.A. Zhussupova4

Zhexenbek Toktarbay5,6

1Institute of Natural Sciences and Geography, Abai Kazakh National Pedagogical University, 13, Dostyk ave., Almaty, 050010, Kazakhstan.
2Department of Chemical Processes and Industrial Ecology, Satbayev University, 22, Satbayev street, Almaty, 050013, Kazakhstan.
3School of Chemistry and Chemical Engineering, South China University of Technology, Guangdong Province 510641, P. R. China.
4Institute of Natural Sciences, Korkyt ata Kyzylorda University, Aiteke bi 29A, Kyzylorda, 120014, Kazakhstan.
5Institute of Ecological Problems, Al-Farabi Kazakh National University, Al-Farabi ave. 71, 050040, Almaty, Kazakhstan.
6Laboratory of Engineering Profile, Satbayev University, Satbayev St. 22a, Almaty 050013, Kazakhstan.
#These authors contributed to this work equally.

Abstract

This work reports an electrochemical sensor for high-sensitivity electrochemical determination of chlorogenic acid. The electrochemical sensor was mainly fabricated from Pt@r-GO@MWCNTs ternary nanocomposites prepared by one-pot method, and the modified material structure was characterized by scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy (EDS) techniques. The electrochemical behavior of chlorogenic acid on Pt@r-GO@MWCNTs/GCE was investigated using cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Due to the excellent electrical conductivity and catalytic properties of Pt@r-GO@MWCNTs nanocomposites, compared with bare GCE, Pt@r-GO@MWCNTs/GCE showed stronger electrochemical response signals towards chlorogenic acid. In a 0.1 M PBS buffer solution at pH 6.0 with an enrichment potential of -0.1 V and an enrichment time of 150 s, the linear range of Pt@r-GO@MWCNTs/GCE for the detection of chlorogenic acid was 0.005 ~ 2 µM and 2 ~ 20 µM, and the limit of detection (LOD) was 0.001 µM. In addition, the sensor also has good selectivity, reproducibility, and stability and has been successfully used for the detection of chlorogenic acid in real serum samples with satisfactory results.  

High-Sensitivity Electrochemical Detection of Chlorogenic Acid Based on Pt@r-GO@MWCNTs Ternary Nanocomposites Modified Electrodes